176 Results for "

Sanguisorba officinalis Linn.

" in MedChemExpress (MCE) Product Catalog:
Products (176)

176 Results for "Sanguisorba officinalis Linn." in MCE Product Catalog:

53
Silvestrol
Silvestrol
0 Images
53 Publications Verification
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Category:  

Agave americana Linn. Natural Products Agavaceae Plants Disease Research Fields Cancer

Target:  

Eukaryotic Initiation Factor (eIF) Apoptosis Autophagy

Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
14
Morusin
Morusin
0 Images
14 Cited Publications
Cat. No.: HY-N0622
CAS No.: 62596-29-6
Synonyms: Mulberrochromene
Category:  

Infection other families Flavonoids Anti-aging Flavones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

NF-κB STAT Bacterial

Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
12
Vitexin
Vitexin
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12 Cited Publications
Cat. No.: HY-N0013
CAS No.: 3681-93-4
Category:  

Cardiovascular Disease Neurological Disease Anti-aging Flavones Metabolic Disease Plants Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Trigonella foenum-graecum Linn. Cancer

Target:  

Autophagy

Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
11
Hematoxylin
Hematoxylin
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11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Leguminosae Caesalpinia sappan L. Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
10
Isobavachalcone
Isobavachalcone
0 Images
10 Cited Publications
Cat. No.: HY-13065
CAS No.: 20784-50-3
Purity:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
7
Magnolol
Magnolol
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7 Cited Publications
Cat. No.: HY-N0163
CAS No.: 528-43-8
Category:  

Cardiovascular Disease Neurological Disease Lignans Plants Magnolia officinalis. Rehd. et Wils. Magnoliaceae Phenols Polyphenols Phenylpropanoids Disease Research Fields Inflammation/Immunology

Target:  

RAR/RXR PPAR Autophagy Bacterial

Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis, is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 µM and 17.7 µM, respectively.
6
Cornuside
Cornuside
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6 Cited Publications
Cat. No.: HY-N0631
CAS No.: 131189-57-6
Category:  

Cornaceae Iridoids Cornus officinalis Sieb. et Zucc. Terpenoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

p38 MAPK NF-κB JNK Cholinesterase (ChE) Acyltransferase NO Synthase Interleukin Related TNF Receptor Prostaglandin Receptor ERK COX

Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation .
4
Asparagusic acid
Asparagusic acid
0 Images
4 Cited Publications
Cat. No.: HY-50730
CAS No.: 2224-02-4
Category:  

Infection Liliaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Asparagus officinalis L.

Target:  

Parasite Endogenous Metabolite

Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
4
Syringaldehyde
Syringaldehyde
0 Images
4 Cited Publications
Cat. No.: HY-N1390
CAS No.: 134-96-3
Category:  

Microorganisms Monophenols Ketones, Aldehydes, Acids Manihot esculenta Crantz Phenols Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

COX

Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis . Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg/mL . Anti-hyperglycemic and anti-inflammatory activities .
2
Methyl vanillate
Methyl vanillate
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2 Cited Publications
Cat. No.: HY-75342
CAS No.: 3943-74-6
Category:  

Microorganisms Monophenols Oryza sativa Linn. Gramineae Phenols Plants

Target:  

Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite

Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
2
Dryocrassin ABBA
Dryocrassin ABBA
0 Images
2 Cited Publications
Cat. No.: HY-N0530
CAS No.: 12777-70-7
Synonyms: Dryocrassin
Category:  

Infection Dryopteridaceae Phenols Polyphenols Dryopteris crassirhizoma Nakai Plants Disease Research Fields

Target:  

Apoptosis Influenza Virus

Dryocrassin ABBA (Dryocrassin) is an orally active phloroglucinol derivative that can be extracted from Phyllopteris officinalis. Dryocrassin ABBA has antitumor and antiviral activity. Dryocrassin ABBA induced apoptosis of human hepatocellular carcinoma cells through mitochondrial pathway mediated by Caspase .
2
Moracin O
Moracin O
0 Images
2 Cited Publications
Cat. No.: HY-N3244
CAS No.: 123702-97-6
Category:  

Neurological Disease Phenols Polyphenols Plants Moraceae Disease Research Fields Inflammation/Immunology Morus alba Linn.

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS)

Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects .
2
Verbenalin
Verbenalin
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2 Cited Publications
Cat. No.: HY-N2014
CAS No.: 548-37-8
Category:  

Infection Iridoids Verbenaceae Terpenoids Verbena officinalis Linn. Plants Disease Research Fields Inflammation/Immunology

Target:  

SARS-CoV Amyloid-β Ferroptosis Tau Protein Caspase Bcl-2 Family

Verbenalin is an orally active terpenoid glycoside that can be extracted from the medicinal plant Verbena officinalis. Verbenalin has anti-inflammatory, antiviral, and neuroprotective effects. Verbenalin has a strong binding affinity to the nsp-12 protein of the SARS-CoV-2 virus. Verbenalin can be used in the research of inflammatory and nervous system diseases such as hepatitis and Alzheimer's disease .
2
Monotropein
Monotropein
0 Images
2 Cited Publications
Cat. No.: HY-N0648
CAS No.: 5945-50-6
Category:  

Iridoids Pyrola calliantha H. Andr. Terpenoids Pyrolaceae Rubiaceae Plants Morinda officinalis How Disease Research Fields Inflammation/Immunology

Target:  

Interleukin Related Keap1-Nrf2 Heme Oxygenase (HO) NF-κB Apoptosis

Monotropein is an iridoid glycoside that can be isolated from the roots of Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model. Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytes. Monotropein has cartilage protective activity. Monotropein can alleviate Cisplatin (HY-17394)-induced acute kidney injury by inhibiting oxidative damage, inflammation and apoptosis through activation of Nrf2/HO-1 pathway and inhibition of NF-κB signaling. Monotropein can be studied in research for osteoarthritis, acute kidney injury and acute lung injury .
1
Luteolin 7-diglucuronide
Luteolin 7-diglucuronide
0 Images
1 Cited Publications
Cat. No.: HY-N7269
CAS No.: 96400-45-2
Category:  

other families Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Phosphatase AMPK

Luteolin 7-diglucuronide is the major flavonoid isolated from Aloysia triphylla and Verbena officinalis .
1
Ziyuglycoside II
Ziyuglycoside II
0 Images
1 Cited Publications
Cat. No.: HY-N0332
CAS No.: 35286-59-0
Category:  

Triterpenes Sanguisorba officinalis Linn. Terpenoids Rosaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Reactive Oxygen Species (ROS) Apoptosis

Ziyuglycoside II is a triterpenoid saponin compound extracted from Sanguisorba officinalis L.. Ziyuglycoside II induces reactive oxygen species (ROS) production and apoptosis. Anti-inflammation and anti-cancer effect .
1
Arnidiol
Arnidiol
0 Images
1 Cited Publications
Cat. No.: HY-N4165
CAS No.: 6750-30-7
Category:  

Triterpenes Terpenoids Dendranthema morifolium (Ramat.) Tzvel. Other Diseases Plants Compositae Disease Research Fields

Target:  

Others

Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .
1
3-Epioleanolic acid
3-Epioleanolic acid
0 Images
1 Cited Publications
Cat. No.: HY-N4290
CAS No.: 25499-90-5
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
1
Methyl carnosate
Methyl carnosate
0 Images
1 Cited Publications
Cat. No.: HY-136150
CAS No.: 82684-06-8
Category:  

Infection Labiatae Terpenoids Samanea saman (Jacq.) Merr. Phenols Polyphenols Diterpenoids Plants Disease Research Fields

Target:  

Bacterial

Methyl camosate is a diterpene isolated from Salvia officinalis or Rosmarinus officinalis. Methyl camosate has potent antioxidant and anti-bacterial activity .
1
11,12-Di-O-methylcarnosol
11,12-Di-O-methylcarnosol
0 Images
1 Cited Publications
Cat. No.: HY-N12492
CAS No.: 25460-12-2
Category:  

Paramacrolobium coeruleum (Taub.) J.Léonard Labiatae Terpenoids Diterpenoids Plants

Target:  

Others

11,12-Di-O-methylcarnosol (Comp 7) is a nolic diterpene lactone that can be isolated from leaves of rosemary (Rosmarinus officinalis L.) .
Assay Types